Iron-sulfur cluster-binding protein ykgf

WebFeb 1, 2024 · Iron-Sulfur (Fe-S) clusters are essential for life, as they are widely utilized in nearly every biochemical pathway. When bound to proteins, Fe-S clusters assist in catalysis, signal recognition, and energy transfer events, as well as additional cellular pathways including cellular respiration and DNA repair and replication. In Eukaryotes, Fe-S clusters … WebAug 10, 2024 · The simplest interpretation assigns the elongated tetragonal structure as the preferred form for Fe 4 S 4+ cores with deformation of sufficiently low energy that crystal packing (or, by inference, protein binding forces) could control the nature of the distortions in specific compounds. 128 The elongated tetragonal structure has four long and …

ykgF - Iron-sulfur electron transport protein

WebJul 31, 2024 · Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. WebOct 19, 2024 · Our data indicate that the iron-sulfur cluster is critical for interaction of human Polε with DNA. Probably, abrogated DNA binding is responsible for the loss of both activities in hPolε CD.... how to scroll with touchpad lenovo https://compassllcfl.com

Iron Sulfur Clusters and ROS in Cancer SpringerLink

WebNov 5, 2024 · IscR (iron-sulfur cluster regulator) is an iron-dependent regulator of isc-suf genes and other genes with a role in iron metabolism. ... Gel-retardation assays showed the binding of regulatory proteins to individual promoters. Our results demonstrated that several promoters in a sense and antisense direction influenced isc-suf expression and ... Web2 days ago · Introduction. Iron is an essential trace element that functions as a cofactor in a wide variety of biological processes, such as oxygen delivery, ATP production, and DNA synthesis and repair, by binding to proteins (1, 2).However, excess iron is toxic owing to its ability to promote the generation of reactive oxygen species (3, 4).Ferroptosis (5), a type … how to scroll with trackpoint

ykgF - Putative oxidoreductase subunit with NAD(P)-binding …

Category:Biogenesis of Iron–Sulfur Clusters and Their Role in DNA …

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Iron-sulfur cluster-binding protein ykgf

Iron-Sulfur Cluster Biosynthesis - RCSB: PDB-101

WebBinding site: 111 [4Fe-4S] cluster 1 (UniProtKB ChEBI) PROSITE-ProRule annotation. Sequence: C: Binding site: 114 ... PTHR10849 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL 1 hit; PROSITE. View protein in PROSITE; PS00198 4FE4S_FER_1 2 hits; PS51379 4FE4S_FER_2 2 hits; Pfam. View protein in Pfam; WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules)

Iron-sulfur cluster-binding protein ykgf

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WebJul 23, 2024 · The relevance of this approach is still testified by (1) its wide use to reconstitute iron-sulfur proteins as shown by papers in recent years: ISCU , Chromokinesin, KIF4A , FNR, and NsrR , and (2) the ability to carry out eukaryotic Fe-S cluster reconstitution by the well-characterized prokaryotic systems and/or its essential components such as ... WebAbstract Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene …

WebOct 8, 2024 · show that thousands of novel binding sites for iron-sulfur (Fe-S) clusters and zinc ions can be identified ... sensing iron and oxygen [10-12], while Zn binding is … WebJul 23, 2024 · When the iron salt is dissolved, adjust the volume to 10 mL ( see Note 7 ). 2. Fe dilution: 1 mM ammonium iron ( ii) sulfate ( (NH 4) 2 Fe (SO 4) 2 ·6H 2 O). Add 25 μL of …

WebDOI: 10.1016/j.tem.2009.12.006 Abstract Iron-sulfur (Fe/S) proteins are a class of ubiquitous components that assist in vital and diverse biochemical tasks in virtually every living cell. These tasks include respiration, iron homeostasis and gene expression. WebIron-sulfur clusters-containing proteins participate in many cellular processes, including crucial biological events like DNA synthesis and processing of dioxygen. In most iron …

WebApr 13, 2024 · HIGHLIGHTS. who: Simone Ciofi-Baffoni and Claudia Andreini from the Magnetic Resonance Center CERM, University of Florence, Via Luigi Sacconi, Sesto Fiorentino, FI, Italy have published the research work: The Intriguing Role of Iron-Sulfur Clusters in the CIAPIN1 Protein Family, in the Journal: Inorganics 2024, 52 of /2024/ what: …

WebFeb 8, 2024 · The iron-sulfur (Fe-S) proteomic platform the team developed allowed them to gain a greater insight into the dynamics of iron-sulfur cluster delivery and binding, according to Professor of... how to scroll with trackpadWebGO:0051536 ! iron-sulfur cluster binding GO:0051539 ! 4 iron, 4 sulfur cluster binding GO:0055114 ! oxidation-reduction process GO:0003674 ! molecular function GO:0005575 ! … how to scroll with two fingers on a laptopWebThe proteins shown here are all part of one of the major systems found in bacteria, termed the ISC system. A similar system builds iron-sulfur clusters in our mitochondria. These … how to scroll with wacom penWebthan a [2Fe-2S] cluster. The site-directed mutation experi-ments suggest that the four cysteine residues are involved in the ligation of this [4Fe-4S] cluster. This iron-sulfur cluster has a unique feature, very high sensitivity to oxygen exposure, which has not been observed on other EPR-detectable iron-sulfur clusters in NDH-1/complex I. how to scrub a computer before sellingWebMar 24, 2009 · Protein Submitted name: Iron-sulfur cluster-binding protein Gene ykgF Organism Bacillus cereus (strain Q1) Status Unreviewed-Annotation score: Annotation … how to scroll words in powerpointWebGene ID: 56560881, updated on 7-Feb-2024. Summary Other designations. 2Fe-2S iron-sulfur cluster binding domain-containing protein how to scrub a computerWebIron-sulfur proteins are involved in various biological electron transport processes, such as photosynthesis and cellular respiration, which require rapid electron transfer to sustain … how to scrub a bathroom floor