The Joint FAO/WHO Meeting on Pesticide Residues (JMPR) concluded that novaluron is unlikely to be carcinogenic to humans. Furthermore, it concluded that it is not a developmental toxicant. The organization established an ADI (Acceptable Daily Ingestion) of 0-0.01 mg/kg of body weight, because of the NOAEL (No Observed Adverse Effect Level) of 1.1 mg/kg of body weight per day for erythrocyte damage and secondary splenic and liver changes. This was established in a 2-ye… WebNovaluron was not irritating to the skin and eyes of rabbits and not sensitizing not sensitizing to guinea-pig skin. In short-term and long-term studies of toxicity, the erythrocyte was identified as the primary target of toxicity attributable to novaluron, with secondary effects apparent in the spleen and less commonly in liver and kidneys.
Posttreatment temperature influences toxicity of insect growth ...
WebJul 22, 2015 · In subchronic and chronic toxicity studies, novaluron primarily produced hematotoxic effects such as methemoglobinemia, decreased hemoglobin, decreased hematocrit, decreased red blood cells (RBCs) (or erythrocytes) and increased reticulocyte counts that were associated with compensatory erythropoiesis. WebThe acute and sublethal toxicities of novaluron, a novel chitin synthesis inhibitor, to a laboratory-reared insecticide-susceptible strain of Colorado potato beetle, Leptinotarsa decemlineata (Say), were determined. Novaluron exhibited excellent residual (120 h LC(50) = 0.42 mg litre(-1)) and good d … small towns in england
Review of the existing maximum residue levels for novaluron
WebMar 10, 2024 · Novaluron is classified as “Not Likely to Be Carcinogenic to Humans”; therefore, EPA does not expect novaluron exposures to pose an aggregate cancer risk. … WebDec 22, 2024 · Although novaluron is an insect growth regulator with a low mammalian acute toxicity and a low risk to the environment and nontarget organisms, toxic effects of novaluron have been reported. However, no studies have yet evaluated the effect of novaluron on reproduction. Therefore, we examined the effects of novaluron on sperm … WebDec 22, 2024 · Although novaluron is an insect growth regulator with a low mammalian acute toxicity and a low risk to the environment and nontarget organisms, toxic effects of … higoply